Jack-
Not really. Only the energy required to build the first one.
IMO, nuclear power is something like what Winston Churchill said about democracy: It's a lousy system, but it's better than anything else we have.

Ultimately, of course, solar, wind and water power will be the answer. But that appears to be a long way off. Until they become massively available, I think that conservation and nuclear power are going to have to suffice.