I'm surprised at heart disease in working or field trial setters - I have not heard of it in the UK, where the workers and FT people refer to the show ring dogs as "bucket-headed great brutes" but the show ring people refer to the others as "ugly little fliers". I'd expect the smaller lighter dog to have less heart trouble. But in general mins are created by inbreeding the runts of litters, and often have bad bone growth. Labs and GSDs are almost invariably hip scored in the UK. Irish Wolfhounds are problems as a re-created breed bred up from elkhounds with various crosses considerably after the true Irish Wolfhound became extinct and I expect the race for bulk to have resulted in defects.