Smaller body guitars are a lot more comfortable to play. They're superior in an ergonomic sense, as many posters have said above.

But which guitar is best for you? Well, that's hard to say. You just have to go play a whole ton of them in a good store, both large and small ones, and find one that speaks to you in a special way. There's no predicting which one it will be. It might be a dreadnought (what you call "standard size") or it might be a smaller body guitar.

There's also no predicting which one will have the better sound. They can vary tremendously when it comes to that, and we all have our own unique tastes anyway when it comes to sound. Generally speaking, the more expensive guitars will have the better sound....but even THAT cannot be given an ironclad guarantee. ;-) AS time goes by we get more and more picky, though, and the price range we look at tends to go up.