I had a carpal tunnel scare and found that most of my problems were caused by the mouse. I tried several and ended up with LOGITECH Trackman Marble FX. Funny looking but effective. I'm not saying that my mouse will work for you. I am saying that there's a lot of variety in mouse styles these days and switching from a traditional mouse worked for me. Also, my carpal tunnel scare made me get really serious about proper arm placement. I found that I needed to keep my entire forearm on a flat surface and religiously use a wrist support in addition to the new mouse.