When Jerry mentioned to the doctor that he had stiffness (no pain yet) in the knuckles of both hands, the response was "I'm not surprised considering what you do for a living" (play folk music). He suggested four possible courses of treatment in order of increasing toxicity. Number one was nothing, number two was alleve, number three was glucosamine without chondroitin and we can't remember what number four was. His comment about glucosamine was that the advertising is way out in front of the science but it does wonders for some people.