The active ingredient of SJW, hypericin, is considered by many researchers to have MAO-inhibiting characteristics. So it is essential to be careful and to follow any advice or precautions given in the labelling. Some pharmaceutical companies, e.g. Merck, are selling their own formulations of SJW and these are OTC, at least in many countries.

It is particularly important not to take SJW with any other prescribed antidepressant.

SJW works with many people but, as with prescription antidepressants, the effects may vary widely from person to person. SJW was ineffective for me and Prozac caused me unacceptable side effects. I was since prescribed venlafaxinum (Efexor) which is effective for me with less severe side effects.

Playing with your brain chemistry without specialist knowledge is dangerous. Please always consult a doctor!

mcmoo