Sorry I wasn't here when someone asked in Aug08 if anyone had tried these with an autoharp. The answer is yes of course, lots of people have, including me. I didn't like them, like Backwoodsman I found they hurt too much, but lots of people do swear by them. I LOVE the Perfect Touch picks, though can be tempted to replace the PT Thumbpick with the Fred Kelly speed pick. I also have arthritic fingers, and the way the PT picks can be bent around to fit individually works fine for me.