You get into all kinds of crap when you try to compare and there are problems but in the main they relate to the solvent tendencies of ethanol and the less power and mileage. If you own a car built in the past ten years that stuff has pretty much been solved by the manufacturers (seal material in fuel pumps for example). So the 10% blends aren't going to matter. Power and economy have obviously been addressed and unless you'd like a dissertation on compression ratios, cam timing, ignition timing, and stoichiometric ratios, don't worry about that either.
IF your car or truck is set up for E85 that's fine. If not and its been built since 2000, the pump gas is fine. Now as far as marine or long term storage goes, that's another story. There might be some problems there but most of this stuff you read is based on old data and scary rumors and anecdotes.........