I go in direct (via a foot switch to effectively turn it off whilst I am waffling between songs) to my mixer desk usually, (24 channel Mack.)

If it is just me, then that's it. (The mixer is a bit OTT for one man bands, but as easy to lug `round and set up as a smaller one.) if I am with a band using my equipment, I have been known to pre mix via a small Alessi mixer that has a set of foot pedals to turn on/ off and clean feed / go via effects unit.

In theatres using their PA, I do have a small DI so they can put the guitar in via a mic circuit.

Mind you, that said, I don't perform regularly these days, so a nice loud acoustic guitar is the norm. (Again, the Rainsong, but also an old Jim Harley dreadnaught I have can fill a room at a folk club. Usually take both, putting the Harley in a different tuning.)