We normally hear this chord pattern,(although it could be in any key) with the rhyming verses over these chords and a vamp on the G while the comments are added at the end.
G |C |D |   |G |C |D |   |G |   |C |   |D |   |G |...
It is usually flat picked with a lot of runs between chords.
Since this is the way Chris Bouchillon, the "Original Talking Blues Man" played it, most talking blues follow this pattern, but there can be variations. I guess any song that is spoken against an instrumental background could be called a talking blues. What about Carson Robison's Life Gets Teejus, Don't It, sung by everyone from June Carter to Doc Watson to Walter Brennon. Most folkies finger-pick this one with an instrumental break.