'some' programs can be moved easily, as they are not installed, but only write to their .ini file. (but you no doubt know that)

Others usually have to be re-installed with a new designated address.

There 'might' be a help in an older program once distributed by PC Magazine called COA "change of address" which helps put them somewhere else and clarify that to the PCs registry.

It is now only on an Italian site where one aficionado saves "rare ware" and one Sourceforge site.

http://digilander.libero.it/rareware/coa2.zip

http://xpt.sourceforge.net/old_home/tools/win/coa32.zip

I have no idea if it is still relevant, but I suspect one might have to totally re-install some things.