The Mudcat Café TM
Thread #145318   Message #3361334
Posted By: Q (Frank Staplin)
09-Jun-12 - 02:18 PM
Thread Name: BS: Lipitor, the multi-billion dollar drug
Subject: RE: BS: Lipitor, the multi-billion dollar drug
Bruce Roth, "superstar among chemists,"
Biography in Iowa State alumni magazine, Visions: "The $12 Billion Man."
http://visions.isualum.org/fall06/coverstory8.asp

Awards include:
1999 Inventor of the Year Award from New York Property Law Association

2003 American Chemical Society Award for Creative Invention

2003 Gustavus J. Esselen Award for Chemistry in the public interest

Iowa State's Distinguished Achievement Award in 2005

2008 American Chemical Society, "Heroes of Chemistry." (25 members, 2008 inductees from Glaxo SmithCline, Pfizer, ExxonMobil, Wyeth Research, Albemarle Corporation.

References include-
Roth BD et al., Inhibitors of cholesterol biosynthesis..... J. Med. Chem, 1991 Jan:34(1):357-66. (The et al. includes his nine co-workers at Warner Lambert).

Roth and the original synthesized of statins, Akira Endo, could well be nominated for the Nobel Prize in Medicine.

Endo A, Hasumi K, 1989, Biochemical Aspect of HMG CoA reductose inhibitors, Adv. Enzyme Regul. 1989:28:53-64.
Endo A, 1988, Chemistry, biochemistry and pharmacology of HMG-CoA reductase inhibitors. Klin. Wochenschr. 1988 May 16;66(10):421-7.

Thanks to my son's physician wife for help with references obtained from PubMed.gov, US National Library of Medicine, National Institute of Health.