My three Siamese look at me with total lack of interest if I screech, point and indicate that they should grab the nasty spider. As they're of tropical origin, I wonder if they're genetically programmed not to touch spiders, which might be venomous in their land of origin. Yet they used to torment poor Hissing Sid mercilessly by poking him with an outstretched paw. He hissed and curled up under a raised pot on the patio, and they'd spend the afternoon prodding him now and then just to wind him up. I had to hold him behind his head hissing like anything, take the tail in my other hand and put him safely in the bank at the bottom of the garden. He was about 5ft long, but I never minded. I've had British cats too, and they weren't interested in spiders either! Only my husband comes willingly to my rescue, bless him.