"Genetic Entropy is the theory that genetic mutations are accumulating to an eventual extinction of all species. The theory was originally proposed by Joseph Muller in 1932 and named Muller's Ratchet[1], he imagined it as a means by which selection forced asexual populations to evolve sexual reproduction. The geneticist John C. Sanford has further expanded on the theory in a more realistic framework from the Biblical worldview, and published the work in a book titled Genetic Entropy & the Mystery of the Genome.[2]"

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http://creationwiki.org/Genetic_entropy