I', right-handed, but play the whistle left-handed - which is a pain in the arse (as it were).
I picked up a three-hole tabo pipe when I was about 14 and started playing around with it and, because the left hand plays down the bottom of the instrument, I kept it there when I started playing the whistle - and there it's remained.
All of which probably explains why I am to whistle playing what Douglas Bader was to tap-dancing, and whcy the first time I tried to play a recorder I thought "What pillock put the holes in the wrong position?"

The trouble with shooting right-handed with a dominant left eye is that you end up with a pug-ugly gun. Instead of a gentle cast in the stock, you end up with something that looks like a serpent.
Interestingly, a lot of the London gunsmiths made some strange looking pieces in the years following the Great War because so many of their customers had come back minus the odd arm or eye.