Von Braun was heavily invested in centrifugal stations.
The ISS crew is always poised and ready to bug out in the event of an enormous solar event.

Its interesting to point out that women's eyes are a bit more robust than men's eyes in space. There are other differences also.

Evolution in as little as a generation could occur when dormant genes wake up. That may indicate previous exposure to the rarified stress of space travel. Imagine a 50,000 year old adaptation we have no idea we already have. This is all far flung speculation but good filler for sci fi.

What other cool stuff do know Bruce?