I assume this drive is USB. If it doesn't work with your box there's little to lose by opening it up. Inside there's probably a 2½" HDD. I have a couple of those USB to SATA adapters - about $5-10: they work. Buy a USB 3.n where n is as high as possible, for future compatibility. If the drive is bigger you'll have to plug it in to a SATA socket on the mobo and a power supply.

If the drive has failed that's probably the end of it.