By mid century global warming will force more agriculture indoors.
CRISPR and AI will make some crops growable by conventional means but the end of the century will find supply failing demand worldwide.

We will of course be dead and not see the ravages of famine. Beans be it quinoa or soy may prove to save mankind.
Its not just crops under threat, it is the declining number of farmers. With luck and policy change, a farmer will not just be a cost to be minimized in the future. More than crops and farmers needing change to survive, bees will also need to be onboard.