Evolution has given us minds that allow us adaptive perceptions but it does not allow us to see reality or the truth. This is why people can easily be misled. Adaptive perceptions are good for survival and reproduction but hide the truth of physical reality.
Our cosmological assumptions grow out of our evolutionary perceptions and are usually wrong. Even spacetime is a human artifact and not a truth. This will always keep human science off balance. New physics will go in geometric dimensions that often defy human consciousness.
We give ourselves a couple basic assumptions and build on that.
We have to see beyond spacetime, the speed of light, and 10 to the minus 33 centimeters. Going beyond conceptual understanding is very hard or impossible. AI is great at coding but having it see beyond itself may not work. Things that break our rules like magic are the inroads that may lead to a new physics. Are 86 billion neurons enough to do that? Goedel's theory of limitation might be right or in 100 years scientists will laugh and mock our current level of understanding.