I once heard a performer say to a heckler, "Ah, yes, I remember MY first beer!" The heckler actually appreciated the humor and applauded along with the audience and nodded his head, as in "Good one. You got me." Well, that's a best-case heckler scenario, so once in awhile you get a heckler who just wants 15 seconds of fame and will shut up at a witty response, especially if the rest of the audience is with you, as in Kendall's experience (that was great, Kendall!). If that fails, I would go with the other's suggestions about the manager.

-chanteyranger