I play Hohner's 12 hole chromatic using a home-made neck brace, while finger-picking a background pattern on guitar. One thing to realize is that the holes on the chromatic are bigger and spaced farther apart than, say, a Marine Band model. So unless you do a lot of slow airs (which is what I prefer) you'll find yourself experiencing a little whiplash if you have to make large jumps up or down the scale. I tried to do The Maid Behind the Bar the other day and damn near got vertigo! ;-)