What you play through will make as much difference3 as what you play. I became very happy playing my electric through the POD. It is an amp simulator...with several built in effects. The range of sounds is enormous and I had to work to narrow it down to a few manageable sounds...but there is always room for growth. Playing out, I could plug the Guitar into the POD and the POD directly into the sound board. It is far less bulky and easier to set up than an amp\mic combo.

AS far as guitars go...listen carefuly for buzzing. I picked up a cheap Danelectro cause I liked the style, but I had to return it the next week. When I tried playing it out at the bar it had a constant buzz (because the wires weren't well shielded?).