I take it you mean the steering wheel is on the right hand side of the car. At least that way you are less likely to wake up in the morning and drive off on the wrong side of the road, which quite often happens to people from Britain using their own cars in France and so forth.

Since everything on the roads is the other way round, that shouldn't be a problem. You might have more difficulty with the controls, because the handbrake and the gear lever (or the automatic controls if its an automatic, which few cars are in Britain) are on your left hand, in the middle of the car.

Also I believe there are some differences in road rules - in normal driving you never overtake on the left, which I believe is legal in America. And remember the petrol is a lot more expensive here than you are used to.

And I read somewhere that you don't normally have roundabouts on American roads. We have lots, and they can be tricky, especially in busy traffic. The basic rule is give way to traffic on the roundabout.