Hi John, i take Glucosamine Sulphate for knee problems (I have arthritis in my knees) i started taking it last winter and it made a big difference, the pain is still there but not as severe, I don't need to take as much Nurufen as I used to.I get my Glucosamine Sulphate from Superdrug, have a look if there is a branch near you (it is a lot cheaper than the local pharmacit).john