I saw a production of MacBeth in the Globe recently that was very odd - the witches wore dinner jackets for example. People lives were symbolised by small balls or stones that were wrestled over. However, this did manage to make one of the lines sensible which is very difficult to act well conventionally:

"They have killed me, mother. Run away, I pray you."

The usual way of doing this is with the victim having a clearly fatal wound, but it still seems to get chuckles from the audience.