re insuline:

The most common sources for insulin, at least by the time it was more than a laboratory curiosity, were pork (swine) and horse (equine) sources. So far as my "fairly modern" references indicate, insulin from sheep has not been commonly used since at least the 1950s(?). At least one company still produces insulin from pork (Betin H by Lilly). Other "large animal" sources have been pretty much eliminated due to the frequency of allergic reaction to the "animal" components.

Depending on your definition of animal, most "modern" insulins still are an animal - bacteria - product. Bacteria that have been genetically modifed to produce "real" human insulin are the source for most insulin used today.

John