Try choosing out of the thousands of publishers which ones to send your book to...just as frustrating, BUT, Bev & Jerry's points are very well taken and also Richie's.

All of the publishing sites tell authors to research what they publish first, before them even send in a query.

FWIW, my old sales manager used to tell us the client hadn't said no until they actually kicked us out! Persistance counts, but NOT after they've been clear about it not being a good fit.:-)