For me, it was deep but at least a decent percent of it was "situational"--- in that my body was falling apart for the last two decades. Those physical symptoms were misdiagnosed --- and that led to all four spinal surgeries with continued degradation of my total health with more misdiagnosed episodes of a bewildering negative nature. Suicide seemed a good way out before total poverty reared it's head. (As I've said, jokingly, "Suicide is the sincerest form of self criticism.) My brother made me see what was happening and we got help--and medication. Then Mayo Clinic found I'd had MS since about 1980. It was liberating !!

And MS itself has cognitive aspects that cause depression. Observable with MRI, placques on the brain and spinal cord can be the culprits here. Recent memory problems are very real too with MS---much more than simple aging. I do believe that is why I continually re-post lines and jokes etc. here in this good forum. ;-)

But Zoloft has helped unbelievably. Along with important talk therapy, my many "losses" of many physical things I once could do easily (like picking) had to be grieved and dealt with much like your loss here, Naemanson.

Don't blow off your dark feelings and the suicidal compulsive hands that are possibly, you think, reaching for you----if indeed they are.
If you, or any others who are depressed, need intervention, get it.

Art Thieme