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86 messages

BS: open mike in hospital

02 Mar 07 - 03:13 PM (#1984243)
Subject: BS: open mike in hospital
From: open mike

i checked into the Emergency Room on wed. p.m.
after experiencing chest pains and difficulty
breathing. the diagnosis is a blood clot in
my lung. Pulmonary embolism (P.E.) is no joke.
but at least it was not a heart attack. or a poke
in the eye with a sharp stick.

i was admitted to the hospital and put on blood
thinners. luckily there is wireless internet
here and my daughter has loaned me her lap top
so i can check e-mail and mudcat!

to have to be here for a week without access
to the internet, mudcat and e-mail would be
a real tragedy!!

i am listening to NPR radio via the net,.\
that beats being at the mercy of the network
television stations!

i was supposed to join my friend buckwheat
bob at several gigs -- today i am missing
the first one--i progress now.

Laurel


02 Mar 07 - 03:15 PM (#1984244)
Subject: RE: BS: open mike in hospital
From: fat B****rd

Best thoughts from Charlie.


02 Mar 07 - 03:21 PM (#1984251)
Subject: RE: BS: open mike in hospital
From: Gizmo

All the best wishes for a speedy recovery.

Well wishes and thoughts

From Nicci


02 Mar 07 - 03:26 PM (#1984254)
Subject: RE: BS: open mike in hospital
From: Scoville

Whoa, I actually came here expecting snide surgery jokes; boy, do I have egg on my face. PE is scary stuff. Wishing you the best.


02 Mar 07 - 03:31 PM (#1984261)
Subject: RE: BS: open mike in hospital
From: Alaska Mike

Laurel, take it easy and follow the doc's instructions. I know how lousy hospitals can be, but I also know they can be very helpful in staying alive. Best wishes for a swift and complete recovery.

Mike


02 Mar 07 - 03:32 PM (#1984263)
Subject: RE: BS: open mike in hospital
From: GUEST,michaelr

Bset wishes for a speedy recovery, Laurel.

Cheers,
Michael


02 Mar 07 - 03:35 PM (#1984271)
Subject: RE: BS: open mike in hospital
From: Deckman

Good Grief Laurel!!! Some folks will do ANYTHING to get attention! It's not often I say that hospitals can be good for you, but I'm sure you realize that where you are right now is the best place possible. I'll let Miken know when he gets home.

So, try to relax, follow orders ... tough as that sounds ... and remember that all of these kind of experiences build "charactor." CHEERS, Bob(deckman)Nelson


02 Mar 07 - 03:36 PM (#1984273)
Subject: RE: BS: open mike in hospital
From: Hawker

Get well soon, Love and kind thoughts, Lucy


02 Mar 07 - 04:06 PM (#1984301)
Subject: RE: BS: open mike in hospital
From: Sorcha

Geeze, Laurel! Get WELL!


02 Mar 07 - 04:07 PM (#1984302)
Subject: RE: BS: open mike in hospital
From: open mike

thanks for all good thoughts
following orders is difficult
but in this case, worth it
i am in good spirits
except that it hurts to laugh


02 Mar 07 - 04:18 PM (#1984307)
Subject: RE: BS: open mike in hospital
From: Deckman

Hey Laurel ... Did you hear the one about the Billy Goat that was seriously attracted to a Republican ... ooops, I'd better not finish it. I might make you laugh! Bob


02 Mar 07 - 04:21 PM (#1984311)
Subject: RE: BS: open mike in hospital
From: kendall

I'm sorry to hear this, and I hope for a speedy recovery.


02 Mar 07 - 04:24 PM (#1984312)
Subject: RE: BS: open mike in hospital
From: Megan L

Lassie get weel soon an thats an order :)
keeping you in our thoughts and prayers.


02 Mar 07 - 04:32 PM (#1984315)
Subject: RE: BS: open mike in hospital
From: Joybell

Healthy thoughts and best wishes, Laurel. Enjoy the getting waited on bit and good luck with the scary bits.
Love Joy


02 Mar 07 - 04:43 PM (#1984324)
Subject: RE: BS: open mike in hospital
From: Wesley S

Yes - behave and follow orders. And that's tough advice to give OR follow.


02 Mar 07 - 04:59 PM (#1984333)
Subject: RE: BS: open mike in hospital
From: Amos

Glad you have your lungs in hand, sweetie!! Keep on breathing!!



A


02 Mar 07 - 05:02 PM (#1984338)
Subject: RE: BS: open mike in hospital
From: Bee

Hope they let you out very soon.


02 Mar 07 - 05:03 PM (#1984339)
Subject: RE: BS: open mike in hospital
From: wysiwyg

No gigs while yer in there! No radio shows from bedside, either-- rest, rest, and more rest, young lady, or we'll send Spaw to tie you to the bed.

~Susan


02 Mar 07 - 05:42 PM (#1984362)
Subject: RE: BS: open mike in hospital
From: ranger1

Get well soon.


02 Mar 07 - 05:52 PM (#1984370)
Subject: RE: BS: open mike in hospital
From: George Papavgeris

All the best, Laurel, we're all thinking of you


02 Mar 07 - 05:54 PM (#1984372)
Subject: RE: BS: open mike in hospital
From: katlaughing

Geez, Laurel, I am glad you went to the ER and that it was not a heart problem, too, but geez. No picnic, I know. Thanks to your daughter for lending her laptop and to you for keeping us posted.

I am sending you lots of healing thoughts and giving thanks for a complete and speedy recovery.

luvyakat


02 Mar 07 - 06:49 PM (#1984406)
Subject: RE: BS: open mike in hospital
From: catspaw49

It's important that you follow directions and take your thinner regularly, having it checked often as well. I hope they can find the reason such as a Factor 5 problem or something as it makes it easier over the long haul.

I am certainly not trying to scare you Kiddo.....But you know just how serious that was/is! They have never been able to isolate the problem that caused Karen's P.E. and subsequent clots but she does her warfarin/coumadin and things are great.

You'll be great too I'm sure and you have all our best thoughts coming your way!!!

Spaw


02 Mar 07 - 07:14 PM (#1984438)
Subject: RE: BS: open mike in hospital
From: skipy

I'm sorry to hear of this, and I wish you a speedy recovery.
Skipy


02 Mar 07 - 08:27 PM (#1984483)
Subject: RE: BS: open mike in hospital
From: open mike

it doesn't help to know that they are giving me rat poison
---do you suppose it is a plot???!!!

better than crushed glass, i guess!!

it is good to know that i am not alone

i may have missed my gig today but plan to
be back in the swing of things by this time
next week...
good lord willing and the creek don't rise.

i will have to look into the 5 factor
whatever that is.

there is an issue with Vitamin K
that i need to learn about...\
as well as avoiding cranberry juice
green tea, garlic and shed loads of
stuff that i have been thinking of
as good for years....

it seems as if vit. K levels go
down with heat...and cooking
may destroy it...if i am correct
...any opinions on this?


02 Mar 07 - 08:37 PM (#1984493)
Subject: RE: BS: open mike in hospital
From: RangerSteve

Life without Cranberry Juice? You really have my sympathies. My thoughts and prayers are with you.


02 Mar 07 - 08:55 PM (#1984507)
Subject: RE: BS: open mike in hospital
From: Deckman

HEY ... DON'T KNOCK CRUSHED GLASS I love it! Bob


02 Mar 07 - 09:09 PM (#1984518)
Subject: RE: BS: open mike in hospital
From: The Fooles Troupe

Best Wishes!


02 Mar 07 - 09:45 PM (#1984547)
Subject: RE: BS: open mike in hospital
From: catspaw49

Ah...the joys of Coumadin.

Coumadin comes in various size pills and you will take it daily. THe amount varies with the individual, their condition, weight and other things but what becomes very important is diet. The Coumadin clinics and other monitoring specialists will try to get you away from some things and blah, blah......What is important is that whatever you eat, you're consistent!

Green leafy stuff contains Vitamin K and K kills the effect of the coumadin. If you're a real veggie nut than cutting back may be in order a it since you want to try not to have too high a daily dose of coumadin. Karen and I both eat veggies like Sprouts and cauliflower and broccoli and spinach which are major coumadin killers but we limit the times per week and the serving size to try to be about the same amount every week......consistency!

The same is true with cranberries, papaya, grapefruit, and other things which ENHANCE the effect of the coumadin. You can still eat about whatever you want but eat it consistently!

You'll get to know all about the numbers especially one called pro-time number which gauges the time it takes blood to clot. Normal clotting blood is around 1.0 to 1.3 or thereabouts. Your doctors will figure a level based on your condition that they want to establish as your number. Karen and other P.E. patients are generally about 2.5 although some Docs vary that. In my case with the heart valve, mine is best kept a bit thinner at 3.0-3.4. To maintain that with a consistent diet I take 7.5mg every day but Sunday and Wednesday when I take a 3mg. Karen weighs less and maintains a lower number but she requires a 7.5 daily.......we're all different. Adjuisting to the proper level can be frustrating at times but its no big deal.

What is a big deal is that you need to get yourself a MED ID something or another so if you're injured the folks working on you will know you take blood thinners!

There is plenty of info a lot better than this on the net and I am sure your Docs will give you reading material as well. Don't be freaked over it......it beats the alternative!

Spaw


02 Mar 07 - 09:49 PM (#1984551)
Subject: RE: BS: open mike in hospital
From: open mike

got any good doctor jokes??

or nurse jokes?

i have a portable heart monitor thingy
telemetry.....sounds like something from star trek..
beam me up...

and i just had a nurse-type person run in to check to see if
i am still alive -- one of the wires came loose from the lead.

luckily i could give her a positive report on my status...
not dead.....yet...... although i sort of wished i was when
every breath was so painful.

the stickers that hold the clips to the wires never come
off though...there are some stuck to the bed nd they will
not peel off no matter what...the stickers last thru showers
and everything...

gosh i wish the lady down the hall was not moaning and wailing.
sometimes she ramps up into an operatic pitch..
sorry if that offends any opera fans out there.

she gives opera a bad name!!

well, i got my mandolin delivered today
so maybe i can echo back with some noise
of my own!!


02 Mar 07 - 10:56 PM (#1984603)
Subject: RE: BS: open mike in hospital
From: Sorcha

Go for it Laurel! But what you really need for that is a Hawaiian lap steel. Do some serious wailing!


02 Mar 07 - 11:00 PM (#1984609)
Subject: RE: BS: open mike in hospital
From: katlaughing

Pick it, gyrl!

Spaw about summed up the coumadin thing. I have been taking since geting the new aortic valve. I do not like taking it, but it beats the chances of the alternative.:-) I found the more I exercised the lower the dosage which flies in the face of their studies, according to the people at the coumadin clinic I go to, but my doc says he thinks it's because my body is using it more efficiently which works for me! My protime has to be between 2.0-3.0. It may take them some time to get your dosages correct. I have finally had my first three months with a steady "read" and so have a set dosage, 7.5 each day except Friday when I only take 5.0.

They are supposed to be developing new drugs for this. Last I heard over in the UK, but who knows? Anyway...you've got the right attitude and I know you are getting better. Just don't come outta there like a horse in a race okay? Take it a little slow and easy. After a week of being in hospital, everything may be a little slow on the uptake and you'll need to be patient with yourself.*smile*

luvyakat


02 Mar 07 - 11:05 PM (#1984611)
Subject: RE: BS: open mike in hospital
From: Janie

Good golly, girl, how frightening! glad you went to the ER and are getting prompt intervention.

Good thoughts and healing energy going up.

Janie


02 Mar 07 - 11:16 PM (#1984615)
Subject: RE: BS: open mike in hospital
From: JennieG

Keep smiling Laurel! don't let them medical folks get you down.

Cheers
JennieG


03 Mar 07 - 12:35 AM (#1984644)
Subject: RE: BS: open mike in hospital
From: Alice

Wow, Laurel. I had a similar experience years back. I'll send you a PM.
alice


03 Mar 07 - 12:38 AM (#1984646)
Subject: RE: BS: open mike in hospital
From: Elmer Fudd

What a bummer, Laurel. Illegitimatus non carborundum! We gotta get Anna Pigeon to kick some serious butt and spring you.

Sending healing thoughts your way,

Elmer


03 Mar 07 - 04:12 AM (#1984691)
Subject: RE: BS: open mike in hospital
From: Liz the Squeak

I know what you mean about those stickers! Waking up in the middle of the night with people standing over you with the adrenalin shot and the paddles is no picnic either!

Have a rest, do what they tell you and don't eat the yellow crap they give you, it's disgusting!

LTS


03 Mar 07 - 05:29 AM (#1984713)
Subject: RE: BS: open mike in hospital
From: Black Beauty

So sorry to hear you were unwell Mike. Get better soon.

Love

Charlotte


03 Mar 07 - 05:40 AM (#1984721)
Subject: RE: BS: open mike in hospital
From: jacqui.c

That was some shock! Take care of yourself Laurel, you know that your friends on the 'Cat will be pulling for you.

Problem is, hospitals are no place to be when you're sick - t0o much noise and dreadfull food most of the time.

Where will you be going when they let you loose? I hope that you have someone to keep an eye on you then - I know that your home is quite isolated.


03 Mar 07 - 06:29 AM (#1984746)
Subject: RE: BS: open mike in hospital
From: gnu

Laurel! Follow all those orders! And get well soon.

Thoughts and prayers.


03 Mar 07 - 10:22 AM (#1984954)
Subject: RE: BS: open mike in hospital
From: Leadfingers

Doctor / Nurse Jokes ?? DONT Tempt me !! Though I could PM you one or two ! Good Vibes from here Laurel !


03 Mar 07 - 11:01 AM (#1984975)
Subject: RE: BS: open mike in hospital
From: katlaughing

Elmer Fudd, gotta get Anna Pigeon outta her latest scrape, first!**bg**

Laurel, how's your morning? Better and freer of pain, I hope.

kat


03 Mar 07 - 11:13 AM (#1984978)
Subject: RE: BS: open mike in hospital
From: John MacKenzie

Laurel I'm not sure a mandolin in hospital is a good thing. I remember my Doc saying, "If you pick it, it'll never get better"

Go get better quick or else.
Giok (((((((L)))))))


03 Mar 07 - 01:38 PM (#1985077)
Subject: RE: BS: open mike in hospital
From: open mike

thanks my friends...
it is hard to jsut sit here.
and harder yet to think about
going back to my little cabin in the woods
where last i was there,
the power and phone were out.

no doubt those things are fixed by now
and perhaps some of the snow is melted.


ok--med time and vitals--see you later


03 Mar 07 - 01:44 PM (#1985084)
Subject: RE: BS: open mike in hospital
From: Alba

Laurel ma Dear.
Och that was a bit of fright for you... and us
You're in the right place for now...honest.
Heal well and keep us up to date with what's happening.
I am holding you in my Heart and in my thoughts.
Loads of Positive stuff and Love:)
Judi x


03 Mar 07 - 01:44 PM (#1985085)
Subject: RE: BS: open mike in hospital
From: AllisonA(Animaterra)

Sending good healing wishes your way- I'm glad you've got your mandolin and your laptop! Think of it as a spa week- lots of pampering and attention, and you can play and cruise the web all you want!


03 Mar 07 - 05:14 PM (#1985225)
Subject: RE: BS: open mike in hospital
From: open mike

this could be habit forming


03 Mar 07 - 08:58 PM (#1985396)
Subject: RE: BS: open mike in hospital
From: leeneia

Best wishes, and I'm glad you got to the hospital in time.

As for the long term, there are worse things than having to do without broccoli, cauliflower and spinach.

Or was Spaw just trying to cheer you up?


03 Mar 07 - 09:05 PM (#1985406)
Subject: RE: BS: open mike in hospital
From: Deckman

During your "spa week" I sure hope that they don't have a fire alarm sound! I can just see you running down the hall. tubes and bottles trailing, and yelling for the truck to get started! SHEEEEUH! Bob


03 Mar 07 - 10:19 PM (#1985453)
Subject: RE: BS: open mike in hospital
From: Ebbie

I'm glad you have your laptop. Feel free to complain all you want- that's when we'll know that you're rapidly getting better.


04 Mar 07 - 12:00 AM (#1985499)
Subject: RE: BS: open mike in hospital
From: open mike

Try to get the I.V. nurse
to arrange your tubes and
lines to facilitate mandolin
picking--no,not on that arm,
no not in that hand, please
move the tape so i can bend
my wrist...

i promised a concert if it
worked right, and so they
fixed me up!

ahhh---music therapy!


04 Mar 07 - 01:08 AM (#1985529)
Subject: RE: BS: open mike in hospital
From: Peace

Lucky for you it's not a banjo.


04 Mar 07 - 05:49 AM (#1985599)
Subject: RE: BS: open mike in hospital
From: Liz the Squeak

Or a melodeon....

Or is that lucky for everyone else?!

Hope you continue to improve dear, ever thought of taking up cross stitch? I find it very theraputic - especially the bundling it up and throwing it across the ward when it goes wrong!

LTS


04 Mar 07 - 06:39 AM (#1985625)
Subject: RE: BS: open mike in hospital
From: Jean(eanjay)

Good wishes sent from Yorkshire. Years ago I had a DVT and I haven't had any problems since.


04 Mar 07 - 03:39 PM (#1986112)
Subject: RE: BS: open mike in hospital
From: Miken

Hi Laurel. Just got home to bob's E-mail. Am thinking good stuff for you and hope you get better and out as soon as possible,and that you have good folks close by at home. As said above, don't let (us) medical folks get you down! :.)
Mike


04 Mar 07 - 03:54 PM (#1986120)
Subject: RE: BS: open mike in hospital
From: Cruiser

Hi Laurel,

I do not know many jokes, however I will say that most men appreciate a good, healthy set of lungs on a woman so get those back in shape and in fine form very soon.

Good luck Lass…


05 Mar 07 - 01:40 AM (#1986558)
Subject: RE: BS: open mike in hospital
From: Partridge

Get well soon Laurel,

love

Pat xx


05 Mar 07 - 02:27 AM (#1986568)
Subject: RE: BS: open mike in hospital
From: Marion

Hello Laurel, and I'm sorry to hear about this. The PE must have been frightening.

So this nurse gets off work and goes to the bank to deposit her paycheque. When she needs to sign it, she reaches into her purse, and pulls out a thermometer. "Oh no" she says... "some asshole's got my pen!"

Marion


05 Mar 07 - 10:54 AM (#1986953)
Subject: RE: BS: open mike in hospital
From: Hollowfox

Good thoughts now $#@!-reduction candle series to start when I get home. You've got a great kid, loaning the laptop. (Mine probably would if they had to, and I threatened to pull it from their cold, stiff fingers if they didn't loan it to me. *g*) It shows you're a Good Mom. As for the jokes, perhaps you could set up, er, an open mike for the staff sometime.


05 Mar 07 - 12:23 PM (#1987101)
Subject: RE: BS: open mike in hospital
From: Donuel

Sorry, the news was slow to reach me.

As boring as convelesing can be you have to admit that dodging; a bullet, lightning bolt, blood clot - is very exhilerating.

You are one of the real good guys (not like the rest of those mudcat posers ;)

We all need you to get up and at 'em real soon.


06 Mar 07 - 12:20 AM (#1987756)
Subject: RE: BS: open mike in hospital
From: Mudlark

Good grief, Laurel! So sorry to hear you're in hospital, but TG you caught problem in time. Sending lots of good vibes and healing thoughts, and an open invite to visit. Power on here and no snow. It's springtime in the lowlands...sun, warmth, and the frogs are singing from the river.   Love, Nancy


06 Mar 07 - 01:09 AM (#1987781)
Subject: RE: BS: open mike in hospital
From: Peter Kasin

So glad they caught it and dealt with it, open mike! Sending all my best to you. I'll watch this thread for further news.

Chanteyranger


07 Mar 07 - 02:05 AM (#1989105)
Subject: RE: BS: open mike in hospital
From: GUEST,neighmond

Lord, you better behave. I sure as hell don't want to be singing Give Me the Roses (while I live) if you aint alive to give the roses! Onrayness!

Pax Vobiscum

Chaz


07 Mar 07 - 03:53 AM (#1989160)
Subject: RE: BS: open mike in hospital
From: Wordsmith

Sorry to hear you're ill, but recuperating nicely by the sound of it. It must be a pretty good hospital to recognize a pulmonary embolism so quickly. You are very lucky. You've also gotten very good advice in this thread. I'm sure you can request to talk to the dieticians before you leave the hospital for guidelines as well as your pharmacist and doctors about interactions and foods. Write down any questions you might have as they arise or you may forget them. Realize you may bleed easier so avoid risky behavior, too. No vigorous teeth brushing, etc. Don't worry, though, you'll adjust. You are very lucky! Best wishes.


07 Mar 07 - 07:46 AM (#1989307)
Subject: RE: BS: open mike in hospital
From: Sorcha

So, can you go home yet? When?


07 Mar 07 - 12:50 PM (#1989628)
Subject: RE: BS: open mike in hospital
From: Zany Mouse

Gosh, that's a bit drastic! Positive thoughts winging their way to you. Keep us informed.

Luv
Rhiannon and Mick


07 Mar 07 - 01:10 PM (#1989656)
Subject: RE: BS: open mike in hospital
From: open mike

i am still in here
and i think i get to bust out in a couple of days
whenever my blood levels reach the right place.

the kitchen here does not understand vegetarians

and they keep putting brocolli and kale on my plate

oh well as the grateful dead song says: I Will Surive!!


07 Mar 07 - 04:21 PM (#1989865)
Subject: RE: BS: open mike in hospital
From: skarpi

Well my friend I hope you get well soon , what you have is NO
joke , rest well and I will send you thoughts and a hug on its way
over the Atlantic
uuuh it might take a while to be there but .........


All the best Skarpi Iceland.


07 Mar 07 - 04:44 PM (#1989891)
Subject: RE: BS: open mike in hospital
From: Deckman

Maybe they put brocolli and kale on your plate as a JOKE? Bob (wait a minute ... aren't those veggies, or have they changed that now)


08 Mar 07 - 01:45 AM (#1990207)
Subject: RE: BS: open mike in hospital
From: open mike

there is a deal about vitimain K
which is found in leafy greens
(brocolli kale parsley
which reacts with the blood thinner


08 Mar 07 - 07:33 AM (#1990351)
Subject: RE: BS: open mike in hospital
From: Sandra in Sydney

when you have to be in hospital, it is a bonus to have a laptop & access to the whole world.

quoting my favourite card "Get well soon, you'll feel better"

best wishes from this side of the pond.

sandra


08 Mar 07 - 08:08 AM (#1990377)
Subject: RE: BS: open mike in hospital
From: Ella who is Sooze

Take care, seriously!

Get better soon, don't lie down flat on the bed, rest, and keep all friends with lurgy (colds etc) away from you!

Best wishes, get better soon...


10 Mar 07 - 12:13 PM (#1992611)
Subject: RE: BS: open mike now home
From: open mike

I made it home safe and sound
the daffodills are blooming
and i am about to have my
first cup of fresh ground
coffee in 1 1/2 weeks!@

i plan to stay away from
sharp objects...the coumidin
has kicked in...but i am
alive, and intend to stay
that way!

thanks for all good wishes.

Laurel


10 Mar 07 - 08:40 PM (#1993079)
Subject: RE: BS: open mike in hospital
From: artbrooks

Hey!! I've been out of town, and not spending much time here. I seem to have missed the whole magilla, but I'm glad that you are in and out again ok. Take care!!


10 Mar 07 - 11:15 PM (#1993147)
Subject: RE: BS: open mike in hospital
From: Bee

Cool! Home and free, and with the added satisfaction of knowing any rat what bites ya will be pizened by the coumadin (or is it the same as Warfarin? Me mum takes so many pills...)!


10 Mar 07 - 11:18 PM (#1993150)
Subject: RE: BS: open mike in hospital
From: Janie

Welcome home!

Janie


10 Mar 07 - 11:38 PM (#1993155)
Subject: RE: BS: open mike in hospital
From: JennieG

Glad to hear you're home! It takes a hospital visit to really appreciate home, doesn't it.

Cheers
JennieG


11 Mar 07 - 12:24 AM (#1993163)
Subject: RE: BS: open mike in hospital
From: katlaughing

Whoo-Hoo! Glad to hear you are HOME. Isn't that a wonderful feeling?! There's a great product to have on hand when taking coumadin (yes, Bee, same thing as warfarin/rat poison:-). It's a spray-on powder which stops bleeding almost immediately. Here's a LINK, so you know what to look for. I think most drugstores sell it.

Take care,

luvyakat


11 Mar 07 - 03:51 AM (#1993203)
Subject: RE: BS: open mike in hospital
From: open mike

yes i may need to lay in a supply of styptic pencil...
and similar....

and here is your trivia question for the day..
where does WARFARIN get it's name?
answer:















Wisconsin Alumni Research Foundation (W.A.R.F.)

The Discovery of Warfarin
One snowy morning in February, 1933, Ed Carlson, a farmer from Deer Park, Wisconsin, came into Karl Paul Link's laboratory carrying a milk-can full of blood that refused to coagulate. Outside he had a small heap of spoiled sweet clover hay and a dead heifer freezing in the back of his truck.

Studies on the factor in spoiled sweet clover hay that killed cattle by hemorrhaging were already well underway on the UW-Madison campus in 1933. R.A. Brink and W.K. Smith in the genetics department had been trying to breed a strain of clover free of the factor's precursor for several years, and efforts to isolate it were underway in Link's laboratory. But Link was an emotional man and, for him, the story of Warfarin really began with Ed Carlson's visit.


The first paper describing the concentration of the hemorrhagic factor appeared in the October, 1940, issue of the Journal of Biological Chemistry. "It was a modest paper," Link recalled. "My rule is, never overstate your case in print. It's better to understate it and let the facts speak for themselves."

In successive papers the facts did so eloquently. In 1941, Link and Harold Campbell reported the isolation of dicumarol, the first of the oral anticoagulants now widely used in surgery and the treatment of circulatory disorders. At the same time, Link was becoming convinced that the anticoagulants being isolated and synthesized in this laboratory might also be useful as rodenticides.

"From the beginning," he said, "I had an intuitive feeling that this might be a good thing. A pretty bad thing for rats, but a good thing for humans. But the idea didn't come overnight. It came into my head and the heads of everyone in the lab over a period of years."

Again, the accumulating facts spoke for themselves, and in 1948 Link came to WARF's director Ward Ross with the suggestion that the foundation patent, as a rodenticide, the coumarin derivative he later named Warfarin.

Why did Link turn over his patents to WARF?

"Well, they couldn't have been developed without the foundation," he said. "I couldn't have done it myself and I never thought of trying."

"And I'm a loyal Wisconsin man," he added. "After all, I went to school here. I came in as a freshman in 1917 and I got all my degrees here. In a broad sense, I wanted to do something for the university."

-- From WARF: Fifty Years, edited by William R. Jordan, III


11 Mar 07 - 09:05 PM (#1993856)
Subject: RE: BS: open mike in hospital
From: Charley Noble

You can't beat being back at home!

And thanks for the info on Warfarin!

Charley Noble


11 Mar 07 - 09:13 PM (#1993861)
Subject: RE: BS: open mike in hospital
From: GUEST,.gargoyle

GET WELL QUICK!~ KID!!

Sincerely in my prayers,
Gargoyle


11 Mar 07 - 09:36 PM (#1993876)
Subject: RE: BS: open mike in hospital
From: bobad

Watch what you eat and keep an eye on your PT times.


12 Mar 07 - 12:35 AM (#1993962)
Subject: RE: BS: open mike in hospital
From: Wordsmith

Glad to hear you're home safe and sound. Thanks for the history of Warfarin, openmike, and also the link to that spray, katlaughing.


16 Mar 07 - 02:03 PM (#1998806)
Subject: RE: BS: open mike in hospital
From: GUEST,Melani

Just saw this--glad you're better!


16 Mar 07 - 03:07 PM (#1998883)
Subject: RE: BS: open mike in hospital
From: katlaughing

Good news on being home and thanks for the history lesson.:-)

Wordsmith, you're most welcome. They have swabs for bloody noses, too.


16 Mar 07 - 03:38 PM (#1998917)
Subject: RE: BS: open mike in hospital
From: Gizmo

Glad your home too.

I hope you recover well, and avoid vit K because it reverses the effects of warfarin.

This was discovered by rat catchers, when it turned out it wasn't doing the job, and it turned out the ratsgot smart and found a way of curing themselves against warfarin. Mice were a bit slower on the uptake however.

This could of course be urban legend bandied around by the rat catchers, but the basis works - vit K is to be avoided.

Glad you're on the mend Laurel.

Nicci


16 Mar 07 - 03:46 PM (#1998919)
Subject: RE: BS: open mike in hospital
From: Bee

I can just see those rat mummies, with their little tiny bottles of green VitK pills to hand around to the ratlings, and the old rat waving a bottle of VitK Fortified Broccoli Beer... "HIC.... darlin' it's for the Warfarin, that's all...."