You can get 50+ years of MAD Magazine from 1952-2006 on 2 DVDs... 600 issues, 17,500 pages. I've just ordered it, not got it yet, so not sure what it's like in terms of quality.
I don't think I've read MAD in decades, but I've fond memories of the late-60s era and can recall several artists - Don Martin, Al Jaffee, Dave Berg, Mort Drucker (the film parodies), Sergio Aragones (the marginal drawn-out dramas) - off the top of my head, which I can't say about many other comic artists (except Frank Bellamy of TV21/Thunderbirds/Zero-X fame. And Her"Tintin"Ge, of course).
When I mentioned MAD-DVD to my brother, he asked how you would get the inside-back-cover foldins to work. I didn't know, but I just found the New York Times, of all places, has a few interactive MAD foldins on their site.